User:Mr. Ibrahem/Vincristine

Vincristine, also known as leurocristine and marketed under the brand name Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. This includes acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer among others. It is given intravenously.

Most people experience some side effects from vincristine treatment. Commonly it causes a change in sensation, hair loss, constipation, difficulty walking, and headaches. Serious side effects may include neuropathic pain, lung damage, or low white blood cells which increases the risk of infection. Use during pregnancy may result in birth defects. It works by stopping cells from dividing properly.

Vincristine was first isolated in 1961. It is on the World Health Organization's List of Essential Medicines. The wholesale cost in the developing world is between US$1.80 and US$42.60 per dose. It is a vinca alkaloid that can be obtained from the Madagascar periwinkle Catharanthus roseus.