User:Mr. Ibrahem/Voclosporin

Voclosporin, sold under the brand name Lupkynis, is a medication used to treat lupus nephritis. It is used in those with severe disease together with mycophenolate mofetil (MMF) and corticosteroids. It is taken by mouth.

Common side effects include high blood pressure, kidney dysfunction, diarrhea, headache, cough, abdominal pain, hair loss, tremor, and mouth ulcers. Other side effects may include high potassium and QT prolongation. It is not typically used in people with long standing poor kidney function or significantly high blood pressure. Use in pregnancy may harm the baby. It interacts with grapefruit. It is a calcineurin inhibitor.

Voclosporin was approved for medical use in the United States in 2021 and Europe in 2022. In the United States it costs about 13,400 USD per month. It is not approved in the United Kingdom as of 2022. It was previously studied for dry eyes.