User:Mr. Ibrahem/Vortioxetine

Vortioxetine, sold under the trade names Trintellix and Brintellix among others, is a medication used to treat major depressive disorder. Effectiveness is viewed as similar to that of other antidepressants. In Britain, it is only recommended in people who have not improved sufficiently on two other antidepressants. It is taken by mouth.

Common side effects include constipation and nausea. Serious side effects may include suicide in those under the age of 25, serotonin syndrome, bleeding, mania, and SIADH. A withdrawal syndrome may occur if the dose is rapidly decreased. Use during pregnancy and breastfeeding is not generally recommended. It is classified as a serotonin modulator. How it works is not entirely clear but is believed to be related to increasing serotonin levels.

It was approved for medical use in the United States in 2013. A month supply in the United Kingdom costs the NHS about £27.72 as of 2019. In the United States the wholesale cost of this amount is about 368.40 USD. In 2017, it was the 312th most commonly prescribed medication in the United States, with more than one million prescriptions.