User:Mxt15/Choose an Article

Article Selection
Please list articles that you're considering for your Wikipedia assignment below. Begin to critique these articles and find relevant sources.

Option 1

 * Article title
 * mTORC1


 * Article Evaluation
 * The mTORC1 article was well written and a great source of information for someone who wants a basic understanding of the function, pathways, and medical relevance of mammalian target of rapamycin complex 1. I don’t have too many concerns regarding the article, but there are two suggestions that I have to enhance the rigor and quality of the article. ·      The article devotes a section to upstream signaling of mTORC1. Specifically they discuss the Akt/PKB pathway, MAPK/ERK pathway, and the Wnt pathway. What more recent literature has shown is the JNK pathway directly activates mTORC1 via phosphorylation of RAPTOR. ·      I would also add more figures and images to enhance the article. The mammalian target of rapamycin complex 1 consists of various proteins. I think it would be beneficial for readers to see a cartoon figure representation of the substrates and proteins associated with the complex. Another figure I would add is a more detailed image of the pathways associated with mTORC1. The general upstream mTORC1 pathway is pretty useful and helpful to understanding the activation of mTORC1, but the downstream pathway could use some more details relating to how it effects transcription.  As a scientific article, the contributing authors do a well job in staying neutral and presenting the facts associated mTORC1. In looking at the references cited at the end of the article, a lot of the papers are older. While this doesn’t hinder the validity of the information presented, it does show that the article may be lacking current and new research that has added to our understanding of mTORC1.


 * Sources
 * MTORC1

Option 2

 * Article title
 * Epigenetic regulation of neurogenesis


 * Article Evaluation
 * This is a very interesting article. The material presented is relevant to the overall topic and interesting to my specific research. As a scientific article, the contributing authors do a good job at writing neutrally. To improve the information in the article, I suggest adding more citations to each claim and having more recent sources. Many of the papers cited in the article are from papers published over 10 years ago, and I believe that with modern technological and scientific advances made there is surly more recent information about the subject.


 * Sources
 * Epigenetic regulation of neurogenesis

Option 3

 * Article title
 * Illegitimate recombination


 * Article Evaluation
 * This article is severely lacking current, creditable and total citations. Following the background paragraph of the topic, the article is split into five sections with each section only having one citation each.


 * Sources
 * Illegitimate recombination

Option 4

 * Article title
 * Cellular stress response


 * Article Evaluation
 * This article was very descriptive about a cell's response to stress factors such as heat and toxins. While I am not too familiar with the topic and don't know all of the cellular stresses, the two presented were adequate.


 * Sources
 * Cellular stress response