User:NDMA in Rantidine

Understanding what is NDMA

NDMA – N-nitrosodimethylamine, A known highly potent human carcinogen.

NDMA is commonly found in Cigarettes, Alcoholic Drinks, Fruits and Vegetables treated with high quantities of Pesticides, and many form of processed foods all known to be direct or indirect cause of increasing cancer.

However, NDMA being very common does not make it less dangerous. Even very low levels of NDMA have been associated with significantly increased risk of cancer.

In fact, NDMA is so dangerous that it is also used to artificially induce cancer in animals, which are used to test the Oncology products.

Recently, Ranitidine (popularly sold by brand names : Zantac, Rantac, Zinetac, Aciloc, etc.), NDMA has been found by Valisure (https://www.valisure.com/) that too, at a very high and concerning levels causing a serious risk of CANCER in patients taking these medicines for Cancer

Ranitidine, considered one of the safest medicine over 40 years, has found to be highly carcinogenic as NDMA is not external impurity, rather it is produced by degradation of Ranitidine molecule when it comes in acidic medium(in stomach). Nitrite and Dimethyline groups break from Ranitidine molecule and produce NDMA.

USFDA has also advised patients to switch to safer molecules like Omeprazole(sold under brand names Prilosec, Losec, Omez, Zegrid etc.) and Pantoprazole (Protonix) with the help of doctors.

13th September, USFDA releases official statement

The U.S. Food and Drug Administration has learned that some ranitidine medicines, including some products commonly known as the brand-name drug Zantac, contain a nitrosamine impurity called N-nitrosodimethylamine (NDMA) at low levels. NDMA is classified as a probable human carcinogen (a substance that could cause cancer) based on results from laboratory tests. https://www.fda.gov/news-events/press-announcements/statement-alerting-patients-and-health-care-professionals-ndma-found-samples-ranitidine