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Chemical-resistant gloves can be made of different kinds of rubber or plastics. The different kinds of rubber are natural, butyl, neoprene, nitrile, and fluorocarbon (viton). The different kinds of plastics are polyvinyl chloride (PVC), polyvinyl alcohol, and polyethylene. Any of these materials can be laminated or blended to create a better performance. There is a general rule when creating gloves, the thicker the material, the greater the chemical resistance. Although, the thicker the glove it may impair grip and dexterity, which can have a negative impact on safety.

Examples of chemical-resistance gloves:


 * Butyl gloves: Made of synthetic rubber and protect against a wide variety of chemicals, such as peroxide, rocket fuels, highly corrosive acids, strong bases, alcohols, aldehydes, ketones, esters, and nitro compounds. They are also resistant to oxidation, ozone corrosion, and abrasion, and remain flexible at low temperatures. Butyl gloves do not perform well with aliphatic and aromatic hydrocarbons and halogenated solvents.
 * Natural (latex) rubber gloves: Comfortable to wear, makes them the popular general-purpose glove. Feature outstanding tensile strength, elasticity, and temperature resistance. These gloves protect workers' hands from most water solutions of acids, alkalis, salts, and ketones. Some people are allergic to Latex and it may not be appropriate for all employees. Hypoallergenic gloves, glove liners, and powderless gloves are good alternatives for workers who are allergic to latex gloves.
 * Neoprene gloves: Made of synthetic rubber and offer good pliability, finger dexterity, high density, and tear resistance. Chemical and wear resistance properties are superior to those made of natural rubber. Protect against hydraulic fluids, gasoline, alcohols, organic acids, and alkalis.
 * Nitrile gloves: Made of copolymer and protect from chlorinated solvents. Nitrile gloves stand up to heavy use after prolonged exposure to substances that cause other gloves to deteriorate. Offer protection when working with oils, greases, acids, caustics, and alcohols. Generally not recommended for use with strong oxidizing agents, aromatic solvents, ketones, and acetates.