User:Naoum.issa

Naoum P. Issa, MD, PhD is a neuroscientist and neurology resident physician. His basic science interests include the development and organization of cerebral cortex, functional mapping methods of brain circuits, and sensory processing. His clinical interests include epilepsy, neurodegenerative diseases, and demyelinating diseases.

Personal Life
Was born in Detroit, MI, USA. Is married to children's author Kate Hannigan. He received his MD, PhD degrees from University of Texas Southwestern, did post-doctoral fellowship at UCSF, was a member of the neuroscience faculty and is a neurology resident at the University of Chicago.

Papers

 * 1) Ringland, J., Issa, N., Schell, M. From U sequence to Farey sequence: A unification of one-parameter scenarios. Phys. Rev. A, 1990, 41:4223-4235..
 * 2) Benser, M. E.*, Issa, N.P.*, Hudspeth, A. J. Hair-bundle stiffness dominates the elastic reactance to otolithic-membrane shear. Hear. Res., 1993, 68:243-252. . * authors contributed equally.
 * 3) Issa, N.P., Hudspeth, A. J. Clustering of Ca2+ channels and Ca2+-activated K+ channels at fluorescently labeled presynaptic active zones of hair cells. Proc. Natl. Acad. Sci. (USA), 1994, 91:7578-7582..
 * 4) Issa, N.P. The concentration of calcium ions at the presynaptic active zone of hair cells during neurotransmitter release. Ph.D. Dissertation, University of Texas, Southwestern, 1995.
 * 5) Hudspeth, A.J., Issa, N.P. Confocal-microscopic visualization of membrane addition during synaptic exocytosis at presynaptic active zones of hair cells. Cold Spring Harbor Symposia on Quantitative Biology, 1996, 61:303-307..
 * 6) Issa, N.P., Hudspeth, A.J. Characterization of fluo-3 labelling of dense bodies at the hair cell's presynaptic active zone. J. Neurocytol., 1996, 25:257-266..
 * 7) Issa, N.P., Hudspeth, A.J. The entry and clearance of Ca2+ at individual presynaptic active zones of hair cells from the bullfrog's sacculus. Proc. Natl. Acad. Sci. (USA), 1996, 93:9527-9532..
 * 8) Issa, N.P., Trachtenberg, J.T., Chapman, B., Zahs, K.R., Stryker, M.P. The critical period for ocular dominance plasticity in the ferret’s visual cortex. J. Neurosci., 1999, 19:6965-6978..
 * 9) Issa, N.P., Trepel, C., Stryker, M.P. Spatial frequency maps in cat visual cortex. J. Neurosci., 2000, 20:8504-8514..
 * 10) Frank, M.G., Issa, N.P., Stryker, M.P. Sleep enhances plasticity in the developing visual cortex. Neuron, 2001, 30:275-287..
 * 11) Silver, M.A., Fagiolini, M., Gillespie, D.C., Howe, C.L., Frank, M.G., Issa, N.P., Antonini, A., Stryker, M.P. Infusion of nerve growth factor (NGF) into kitten visual cortex increases immunoreactivity for NGF, NGF receptors, and choline acetyltransferase in basal forebrain without affecting ocular dominance plasticity or column development. Neuroscience 2001, 108:569-585..
 * 12) Issa, N.P. Inhibitory circuits in sensory maps develop through excitation. TINS, 2003, 26:456-458..
 * 13) Baker, T.I., Issa, N.P. Separable cortical maps underlie population responses to complex visual stimuli. J. Neurophysiol. 2005, 94:775-787..
 * 14) Husson, T., Mallik, A.K., Zhang, J., Issa, N.P. Functional Imaging of Primary Visual Cortex Using Flavoprotein Autofluorescence. J. Neurosci. 2007, 27:8665-8675..
 * 15) Zhang, J.X., Rosenberg, A., Mallik, A.K., Husson, T.R., Issa, N.P. The representation of complex images in spatial frequency domains of primary visual cortex. J. Neurosci. 2007, 27:9310-9318..
 * 16) Grossman, K., Ross, J., Kay, L., Issa, N.P. Glomerular activation patterns and the perception of odor mixtures. Eur. J. Neurosci. 2008, 27:2676-2685. PDF,.
 * 17) Issa, N.P., Rosenberg, A., Husson, T.R. Models and measurements of functional maps in V1. J. Neurophysiol. 2008, 99: 2745-2754. Invited review.
 * 18) Mallik, A.K., Husson, T., Zhang, J., Issa, N.P. The organization of spatial frequency maps measured by cortical autofluorescence. Vision Research 2008, 48:1545-1553. PDF,.
 * 19) Llano, D., Theyel, B., Mallik, A.K., Sherman, S.M., Issa, N.P. An all-optical method for rapidly mapping neural circuits in slice using flavoprotein autofluorescence and laser photostimulation. J. Neurophysiol. 2009, 101:3325-3340. PDF,.
 * 20) Husson, T.R., Issa, N.P. Functional imaging of visual cortex using flavoprotein autofluorescence. Chapter for In vivo optical imaging of brain function, 2nd Ed. Edited by R.D. Frostig. CRC Press. 2009.
 * 21) Rosenberg, A., Husson, T.R., Issa, N.P. Subcortical encoding of second-order image features. J. Neurosci. 2010, 30:1985-1993. PDF,.
 * 22) Theyel, B.B., Llano, D.A., Issa, N.P., Mallik, A.K., Sherman, S.M. Laser photostimulation with flavoprotein autofluorescence imaging in vitro. Nat Protoc. 2011 6:502-8..
 * 23) Rosenberg, A., Issa, N.P. The Y-cell visual pathway implements a demodulating nonlinearity. Neuron 2011 71:348-361..
 * 24) Issa, N.P., Rosenberg, A. Tartini’s devil: Peripheral mechanisms that underlie sensory illusions. Book chapter in: A field guide to a new meta-field: bridging the humanities-neurosciences divide. Ed. B. Stafford. University of Chicago Press, 2011.
 * 25) Assimacopoulos, S., Kao, T., Issa, N.P., Grove, E.A. Fibroblast Growth Factor 8 organizes the neocortical area map and regulates sensory map topography. J Neurosci. 2012 32:7191-7201..