User:Nataliya.pavlyk/sandbox

Transfer of Cholesteryl ester

Cholesteryl ester is transported from high-density lipoproteins (HDL) to low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL) with cholesteryl ester transfer protein (CETP). The decrease in cholesteryl ester can lower HDL and increase LDL, which may be an indicator of cardiovascular problems, as indicated by intervention studies. Increasing HDL values has the potential to prevent mortality associated with cardiovascular risks such as atherosclerosis.

Low HDL --> increased risk of cardiovascular problems. Inhibiting CETP --> Potentially prevent decrease on HDL values