User:NeilTraynor/sandbox

Causes
The most common causes of splenomegaly in developed countries are infectious mononucleosis, splenic infiltration with cancer cells from a hematological malignancy and portal hypertension (most commonly secondary to liver disease). Splenomegaly may also come from bacterial infections, such as syphilis or an infection of the heart's inner lining (endocarditis). Splenomegaly has also been observed in Hemochromatosis patients, possibly linked to Portal hypertension.

The causes of massive splenomegaly (>1000 g) are much fewer and include:
 * thalassemia
 * visceral leishmaniasis (kala-azar)
 * schistosomiasis
 * chronic myelogenous leukemia
 * chronic lymphocytic leukemia
 * lymphomas
 * hairy cell leukemia
 * myelofibrosis
 * polycythemia vera
 * Gauchers disease
 * Niemann–Pick disease
 * sarcoidosis
 * autoimmune hemolytic anemia
 * malaria