User:Neuralia/sandbox/King

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George L. King is an American physician-scientist and Thomas Beatson, Jr. Endowed Chair Professor of Medicine and Ophthalmology at Harvard Medical School. He is also Chief Scientific Officer, Senior Vice President and Head of the Section on Vascular Cell Biology at the Joslin Diabetes Center, where he has continuously worked since 1981. He has published over 350 scientific papers, which have been cited nearly 100 thousand times. These articles mostly correspond to topics in Internal Medicine, Endocrinology and Diabetes Mellitus. His most cited research relates to the treatment of type 2 diabetes with diabetic retinopathy, and the options available to reduce vascular complications of the disease. King received his medical degree from Duke Medical School, undertook residency training at the University of Washington Affiliated Hospitals, in Seattle, and completed his research and clinical training at the National Institutes of Health. He has proposed that an abnormally high activation of protein kinase C (particularly its beta and delta isoforms) is the major signaling disturbance by which hyperglycemia causes insulin resistance and pathologies in the retina, kidney and cardiovascular system of diabetic patients. His current research aims at finding protective biochemical factors acting to prevent complications in a large, special group of medalist type 1 diabetic patients who have remained relatively healthy even after 50 or more years suffering the disease. King also leads a national effort to improve care for diabetes in Asian Americans, who develop diabetes at low body weight.