User:Ngkengwooi/codrug

Definition
A co-drug (or codrug) is a pharmaceutical drug consisting of more than one drug molecules or moieties, each therapeutically active against the same medical condition, that are linked to one another by covalent bonds. Administered in this format, a co-drug is itself therapeutically inactive. It is designed to be metabolized in the body upon administration to liberate the parent drug moieties at an appropriate target site where their therapeutic effects are needed.

The working principles of a co-drug are very similar to those of a pro-drug (or prodrug), with an important difference. Whereas the metabolism of a pro-drug leaves behind by-products which are not therapeutically useful against the target medical condition, all metabolites of a co-drug are therapeutically useful against the same disease.