User:NicoleCzQU/sandbox

Proposed Change: Under the “Sublingual Immunotherapy” heading, add a description of the practical use of sublingual immunotherapy. The original text “Sublingual immunotherapy involves… swallow the extract” would be expanded with the following:

Sublingual immunotherapy is used to treat allergic rhinitis, often from seasonal allergies, and is typically given in several doses over a 12 week period. (1) It works best when given 12 weeks before the start of the pollen season. (1) The first dose is given by a physician to monitor for any rare reactions or anaphylaxis. (1) Subsequent doses can be taken at home (1) which makes this a convenient to subcutaneous immunotherapy. Justification: There is no clear description of sublingual immunotherapy present on this page. The reader may be unable to distinguish sublingual immunotherapy from oral immunotherapy for food allergies. This information was obtained from a meta-analysis of guidelines for sublingual immunotherapy versus subcutaneous immunotherapy in Europe and the United States. This change would give a clearer understanding of the procedure to an interested reader with no background knowledge of the treatment.

Proposed Change: In the “Sublingual immunotherapy” subsection, remove the sentence “For seasonal… small”

Justification: This claim is not substantiated by several meta-analyses. Though the paper citing this claim was recent (2015), other meta-analyses suggest there are notable benefits to sublingual immunotherapy (2,3).

References:

1. Pepper AN, Calderon MA, Casale TB. (2017) Sublingual immunotherapy for the polyallergic patient. J Allergy Clin Immunol Pract, 5:41-5.

2. Aboshady, Omar Ali and Karim Mohamed Elghanam. “Sublingual immunotherapy in allergic rhinitis: efficacy, safety, adherence and guidelines” Clinical and experimental otorhinolaryngology vol. 7,4 (2014): 241-9. 3. Masuyama K, Matsuoka T, Kamijo A. (2018) Current status of sublingual immunotherapy for allergic rhinitis in Japan. Allergology International, 67(3):320-5.

Comments
Thanks for sharing your proposed article improvements.

Please add your citations using the DOI (by clicking "cite" and pasting in your DOI to auto populate the citation template). Citations go immediately after the punctuation, no space like this. [1] JenOttawa (talk) 17:38, 12 November 2018 (UTC)