User:Nicolekonadu/IL-10 family

IL-10 family
The IL-10 family are helical cytokines and are categorized because of their specific similarities. The IL-10 family are classified as class 2 cytokines. The features of the IL-10 family consist of having their genomic structure be similar, having their primary and secondary protein structures be similar, having a clustering of encoding genes, and utilize the similar receptor complexes.

Three Subgroup of IL-10 family
Based on their functions, the IL-10 cytokine are separated into three different groups. IL-10 family cytokine is the first group that selects the innate and adaptive immune response and can prevents the function to reduce tissue damage. The IL-20 family of cytokine subgroup consist of IL-19, IL-20, IL-22, IL-24, and IL-26 and they work on tissues in the stroma and epithelial cells to bring out the mechanism of innate defense to manage the attack of extracellular cellular pathogens. The IL-28 cytokine subgroup including IL-28A, IL-28B and IL-29 are type III interferon (IFN) family. They share intersecting biology and a signaling pathway with with type I IFN cytokine family but the type III INF cytokine family prefer to target the tissues of the epithelial cell.