User:Nishimurar/sandbox

Choline deficiency can lead to health problems such as liver damage, a result of liver cells initiating programmed cell death (apoptosis), as well as an increase in neural tube defects in pregnant women. In a study, 77% of men, 44% of premenopausal women, and 80% of postmenopausal women developed fatty liver or muscle damage due to choline deficiency, showing that subject characteristics regulate the dietary requirement. Choline deficiency has also been associated with hypertension in rats. In order to avoid these problems, it's important to meet the adequate intake, especially since many multivitamins do not contain enough choline. Although many animal products, like liver and egg, contain high amounts of choline (355 mg/3 oz and 126 mg/large egg, respectively), wheat germ (172 mg/cup), brussel sprouts (63 mg/cup), and broccoli (62 mg/cup) are good sources of choline as well. There is also some evidence that choline is an anti-inflammatory as well, but further studies are needed to confirm/refute findings.