User:Oc373/sandbox

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Practice Editing Here (Nov 15th in-class Wiki session work)

 * This is a place to practice clicking the "edit" button and practice adding references (via the citation button).

Task:


 * 1) Find a peer-reviewed journal article on PubMed. Practice inserting your citation in the above space using the "cite" tool
 * 2) Choose one "B-level" medical article on Wikipedia from the following list: https://wp1.openzim.org/#/project/Medicine/articles?quality=B-Class&importance=High-Class
 * 3) Practice editing live on Wikipedia by finding a typo in the text or improving the clarity/readability of a sentence by adjusting a few words in a sentence.

Assignment # 3- please post an anonymous copy here!
Proposed changes:

This is currently written in the ‘prognosis’ section of the Wikipedia article:

“While prognosis is highly variable and dependent on various factors including these mutations, the average 5-year relative survival is 86.1%. Telomere length has been suggested to be a valuable prognostic indicator of survival.”

I would like to add these two sentences:

“In addition, sex has been found to have an impact on CLL prognosis and treatment efficacy. More specifically, females have been found to survive longer (without disease progression) than males, when treated with certain medications.”

These sentences are written in lay terms, do not include medical jargon, and could be understood by someone 12 years of age. No new technical or medical terms are introduced. The word 'patient' is not used.

Rationale for Proposed Changes:

It is currently written on the Wikipedia page that “prognosis is highly variable and dependent on various factors”. An example of telomere length and mutations are given. I believe that it is important to include more examples, specifically one that is easily understood by the general public, such as differences in prognosis based on sex. This is an important prognostic factor and one that readers would benefit from knowing and can easily understand.

Using PubMed, an advanced literature search was conducted using four filters. The search was limited to systematic reviews or meta-analyses written in English over the last five years. The search terms “chronic lymphocytic leukemia prognosis” and “sex” were used, and no search results were found. The search terms “chronic lymphocytic leukemia prognosis” and “gender” were then used, presenting two results. Upon evaluating both results, I selected the paper titled “Impact of gender on outcome after chemoimmunotherapy in patients with chronic lymphocytic leukemia: a meta-analysis by the German CLL study group”. The citation can be found below:

Al-Sawaf, O., Robrecht, S., Bahlo, J. et al. Impact of gender on outcome after chemoimmunotherapy in patients with chronic lymphocytic leukemia: a meta-analysis by the German CLL study group. Leukemia 31, 2251–2253 (2017). https://doi.org/10.1038/leu.2017.221

I don’t believe there would be any controversy affiliated with the changes made. The new sentences are written in a neutral tone without strong language.

Critique of Sources

There are no major issues with the source chosen nor is there concern for bias. An advanced PubMed search was conducted, providing a legitimate source with a well-designed study. One concern could be the fact that the advanced PubMed search only produced two relevant papers. Although the paper selected contains a well-designed meta-analysis, this appears to be the only meta-analysis studying sex differences in CLL prognosis. Due to the fact that the meta-analysis was well designed and didn’t contain bias or leading language, we believe the paper can be trusted and should be used as a citation in the Wikipedia article.



What to post on the Wikipedia article talk page (part of assignment 3)

 * This will also be covered on Nov 15th in class. Your group should use the below template to share an outline of your proposed improvements (including your new wording and citations). Article talk pages are not places to share your assignment answers. The Wikipedia community will be more interested in viewing your exact article improvement suggestions including where you plan to improve the article (which section), what wording you suggest, and the exact citation (Note: all citations must meet WP:MEDRS)
 * You will not be able to paste citations directly from your sandbox to talk pages (unless you are interested in editing/learning Wiki-code in the "source editing" mode). We suggest re-adding your citations on the talk page manually (using the cite button and populating the citation by pasting in the DOI, website, or PMID). You will have to repeat this process yet again when you edit the actual article live.
 * Talk Page Template: CARL Medical Editing Initiative/Fall 2021/Talk Page Template