User:OliviaHall10/Border Cell (brain)

Wikipedia Proposal: Border cell (brain)

Olivia Hall, Patrick Scherer, Greg Zandrow

This is the proposal for our Wikipedia project on border cells in the brain. This is an outline for how the page will appear. Each week we will meet to delegate specific research subtopics and discuss previous findings. Each group member will be responsible for certain subtopics, but we will work together to finalize the product.

Introduction
Border cells are crucial in spatial recognition pathways in the parasubiculum and medial entorhinal cortex. They provide information about boundaries and edges of a field regardless of the orientation of the viewer.

Discovery
We will discuss the discovery of border cells by Dr. Neil Burgess in 2000.

Anatomy
Border cells are sparse and found in the medial entorhinal cortex and the parasubiculum. They are intermingled with head-direction, place and grid cells, which together form a cognitive-spatial map.

We plan to discuss the entorhinal cortex and parasubiculum functions and locations in further detail.

Function
Border cells are thought to be activated in response to the presence of edges of proximal environments. The parasubiculum integrates spatial information from the head-direction, grid, place and border cells. Research also suggests that border cells provide information necessary for trajectory planning.

We plan to discuss the function of both the head-directional and grid cells in further detail, as their function is important in conjunction with the function of border cells.

Research Methods
Brain imaging was integral in determining when and why certain border cells were active, so we plan to discuss how these functional images were interpreted.

Border scores are mathematical representations that were used statistically to determine the activity of border cells in response to changing boundaries. We will discuss how these values were calculated and what they mean.