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= Marie-Hélène Verlhac = Marie-Hélène Verlhac is a French cellular biologist, specialising in the final stages of oocyte development. She was the recipient of the French National Centre for Scientific Research's (CNRS) Silver Medal in 2021.

Doctorate: MAP kinase and meiotic maturation of mouse oocytes (1995)

Personal website: https://www.college-de-france.fr/site/en-cirb/Terret-Verlhac.htm

Verlhac has been the director of the Center for Interdisciplinary Research in Biology (CIRB) (French: Centre interdisciplinaire de recherche en biologie) since 2019, and the president of the French Society for Cell Biology (SBCF).

Life and career
In 1988, Verlhac began her studies at the Ecole Normale Supérieure de Lyon. She graduated from Université Pierre et Marie Curie (UPMC) with a Master in Cellular and Developmental Biology in 1991, followed by a PhD in cellular and molecular biology in 1995, under the supervision of Dr. Bernard Maro. Her PhD studies also included a year studying under Prof. Hugh Clarke at McGill University. She undertook postdoctoral studies with Rik Derynck at the University of California, San Fransisco.

Verlhac returned to France and became a principal investigator of her own lab in 2002, which researches oocyte mechanics and morphogenesis. Oocytes, the female gametes, divide asymmetrically so that maternal stores can be preserved for the embryo's development; Verlhac's lab uses genetics, two-hybrid screening, and live-imaging combined with biophysics to study such divisions. In particular, her lab has discovered the mechanisms underlying the positioning of the nucleus and spindle in oocytes.

Verlhac was appointed deputy director of the CIRB in 2013, then Director in 2019.

Awards and honours

 * The Royal Academy of Science, Letters and Fine Arts of Belgium's Albert Brachet Prize for embryology (2018)
 * Member of the European Molecular Biology Organization (EMBO) (2018)
 * CNRS Silver Medal (2021)

= Medaille de Bronze du CNRS = The CNRS Bronze Medal rewards the first work of a young researcher or teacher-researcher in his or her field. It is an encouragement from the National Centre for Scientific Research (Centre National de Recherche Scientifique, CNRS) to pursue promising research that is already under way.

The bronze medal is awarded on the proposal of a committee of the CNRS, composed of CNRS researchers, university teacher-researchers and engineers. It is awarded each year to around fourty researchers or teacher-researchers from a French public scientific and technological institution, generally one per section of the National Scientific Research Committee (Comité national de la recherche scientifique).

Since 2008, the CNRS has decided to increase the visibility of women scientists and applies a parity principle for the awarding of the bronze and silver medals.

Marion Kay Campbell
CStat, FSS, FFPH, FSCT, FRSE

Fellow of the Royal Society of Edinburgh (FRSE), elected 2013. Also an elected fellow of the Faculty of Public Health and the International Society for Clinical Trials.

Dean of research (Life Sciences and Medicine) and Professor of Health Services Research at the University of Aberdeen.

Appointed Vice-Principal Research at the University of Aberdeen, in October 2017.

She is a medical statistician, and a clinical trialist. Researches the methodology of evaluative research, especially large-scale clinical trials of complex interventions. In particular, the design, conduct and methodological advancement of surgical trials and of cluster randomised trials.

She has served on many national and international funding agencies and committees.

Graduated with an honours degree in Statistics from the University of Aberdeen, then MSc in Statistics and a PhD in Public Health. Early career appointments within the NHS in the fields of Operational Research and Statistics of Medical Audit. Joined the Health Services Research Unit in 1993. Director of the Unit in 2007-2015, then became Dean of Research for Life Sciences and Medicine.

"UK-REBOA: The NIHR-funded UK-REBOA trial aims to establish the clinical and cost-effectiveness of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA), in addition to standard major trauma centre treatment, for the treatment of patients with life-threatening torso haemorrhage.  The trial is currently live across major trauma centres in England.  Further information is available on the trial website: https://w3.abdn.ac.uk/hsru/REBOA/Public/Public/index.cshtml

TOPKAT: The NIHR-funded TOPKAT trial is investigating the clinical and cost effectiveness of partial (PKR) vs total (THR) knee replacements. The trial recruited 528 patients from across the UK. Five year results have been published in the Lancet ( https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31281-4/fulltext) and showed that PKR has similar, if not a slightly better clinical outcome than TKR. More importantly, the economic benefit of using PKR is substantial. Patients are now being followed up to 10 years.

CLASS: The NIHR-funded CLASS trial is assessing the clinical and cost-effectiveness of three treatment modalities for the treatment of varicose veins: a) foam; b) EVLA with subsequent foam to varicosities when required; and c) surgery.  A total of 798 adult patients were recruited into the trial and randomised to one of the treatment options.  Six weeks results have been published in the NEJM ( http://www.nejm.org/doi/full/10.1056/NEJMoa1400781 ).  Five year follow-up is now complete.

KAT: The NIHR-funded KAT trial, explores different knee replacement surgery options (the effects of patellar resurfacing, mobile bearings and metal backing were investigated). A total of 116 surgeons in 34 UK centres participated and 2352 participants were randomised. Ten year outcomes were previously published ( https://www.journalslibrary.nihr.ac.uk/hta/hta18190/#/abstract ); long term follow up to 20 years is underway."

See also: https://www.eveningexpress.co.uk/fp/news/local/surgical-device-trial-helps-trauma-victims/

Henriette Ducros-Rougebief (1889-12-09 -- 1980)
Born 9 December 1989 in Arbois, Jura. Died 1980, Saint-Honoré-les-Bains, Nièvre. Née Rougebief, married Ducros.

Two sisters: Henriette and Germaine Rougebief. Humble background: parents were farmers. Worked as domestic staff to pay for their studies. Studied at the Faculté des Sciences in Besançon. René Vallery-Rado (Louis Pasteur's son-in-law) introduced her to Edmond Sergent, who was the director of the Institut Pasteur in Algiers.

Attachée aux services médicaux, assistante, puis chef de laboratoire à l'Institut Pasteur d'Algérie de 1925 à 1962.

Worked on BCG, Drosophila, and TB. Led a vaccination campaign against BCG in Algiers.

Thesis: Recherches sur les rapports biologiques existant entre les drosophiles et les principaux micro-organismes du raisin, levures et moisissures : thèses présentées pour obtenir le grade de docteur ès sciences de l'Université de Besançon. (Research on the biological relationships between fruit flies and the main grape microorganisms, yeasts and moulds: theses presented to obtain the degree of Doctor of Science from the University of Besançon.) From 1928.