User:Orangtip

My profile

I am Yali Xue, a scientist on the Human Evolutionary Population Genetics in the Human Evolution Team, the Wellcome Trust Sanger Institute. Focus on working on human genetic variation. I was working initially on Y-chromosomal diversity, including involvement in the Genographic Project. Subsequently, focused more on identifying signatures of positive selection in the human genome. Since 2008, I have concentrated on applying new sequencing technology to address human evolution and population genetics questions, e.g. directly measuring Y mutation rate. Involved in the 1000 Genomes Project, including Y-chromosomal diversity, a genome-wide scan for Positive selection, identifying disease variants in the general population, and functional prediction of the consequences of variants.