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Dr. Mario & Puzzle League is a 2005 puzzle video game compilation published by Nintendo for the Game Boy Advance. The game contains the games Dr. Mario and Puzzle League. The game was released in September 2005 in Japan, and subsequently in Europe and the United States in November of the same year.

Gameplay
Dr. Mario & Puzzle League contains modified versions of the games Dr. Mario and Puzzle League.

Dr. Mario
In Dr. Mario, the player must place falling dually-colored pills thrown by Dr. Mario in a bottle full of colored viruses. The colors of the pills and viruses come in red, yellow and blue, and the player must match like colors in sets of four or greater to remove viruses and placed pills. The general aim of the game is to clear all viruses from the bottle. Dr. Mario & Puzzle League offers multiple modes in both single player and multiplayer. In single player, there is "Classic", where the player must complete endless levels until they fail; "Vs. CPU", where the player must duel artificial intelligence in a revised version of Dr. Mario where the first to clear all viruses in their bottle wins the game; "Flash", where the player must duel against artificial intelligence in a fashion similar to "VS. CPU", but instead of clearing all viruses, the winner of the game must clear the viruses that flash. "Classic" and "Flash" are also offered in multiplayer. Dr. Mario offers similar level of customization to the original game; the player can adjust the level of difficulty, the speed that pills fall on and the song that plays during gameplay. Additionally, in comparison to past Dr. Mario games, the bottle is only thirteen spaces tall rather than the typical sixteen.

Puzzle League
Most similar in fashion to Tetris Attack, in Puzzle League, the player must swap tiles on a horizontal axis to match them with like colors in order to clear them on a 12 by 6 grid. The player must match these


 * https://www.gamespot.com/reviews/dr-mario-puzzle-league-review/1900-6141121/
 * http://www.eurogamer.net/articles/r_drmariopuzzle_gba
 * http://au.ign.com/articles/2005/11/28/dr-mariopuzzle-league
 * http://www.jeuxvideo.com/news/2005/00014435.htm