User:Peterzarea/sandbox

{{dashboard.wikiedu.org sandbox} The Alpha-Actinin-3 gene has big effect in the life of the athletic people and how it is important in the body during the sports games (athletics). After I read about the Actin 3, I found the athletics successes of the best players are not stopping only for the blood, sweat, hard work, or the good diet for the players and determination plays an important role for the player, but there is the most important thing and essentially which helping the players to be the best and success in the sports that are the Alpha-Actinin-3 gene. Also, it is known with the speed gene in the body of the athletic people. Actin 3 is responsible for the formation of the skeletal muscles in the athletic body. The Alpha-Actinin-3 gene determines the high content of high-fiber muscle and a significant contraction rate of entire muscles. Actin 3 helps the muscles in everywhere in the player’s body to have many these fibers that is helping the player to run so fast for a long time, but if protein Actin 3 decreases in the muscle, the players can not make a good sprinting ). In addition, Alpha-Actinin-3 expresses the rapid muscle fibers that depend heavily on the mobilization of glycogen stores in the cells to stock the energy needed for the constriction. The glycogen is used as a source of energy for its ability to change the state of independence of the muscle . Next, Alpha-Actinin-3 protein is directly expressed in the benign muscle fibers, and the homogenous heterogeneity of polymorphisms is widespread in the ACTN-3 gene that will have a big shortage of the Alpha-Actinin-3 gene in the 1 billion individuals’ person around the world . Now, the genetic studies refer to the absence of the ACTN-3 that will have a bad effect on the players of the running (race), power performance in the athletes, and in the general public. Also, when the α-Actinin-3 decreases, it will be useful and has a positive effect on the endurance sport. Then we used two types of the mouse (knockout (KO), and wild-type (WT)) to see the effect of the α-Actinin-3 when it decreases or not decreases. This experiment helps us to know that the deficiency in α-Actinin-3 will lead to a quick twitch, and the developing fiber will germinate slowly. Allen, DG, et al said: “These changes in the contractile properties of fast-twitch skeletal muscle from α-actinin-3-deficient individuals would be detrimental to optimal sprint and power performance, but beneficial for endurance performance”. In my opinion, the ACTN-3 has positive and negative effect in some athletics, but the some important for the people who like to make race and playing soccer because it helps muscles to endure.