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Peter N. Devreotes (born April 22, 1948) is a Professor and Director of the Department of Cell Biology at the Johns Hopkins University School of Medicine. He has joint appointments in the Department of Biological Chemistry and the Center for Cell Dynamics (CCD) and is a member of the Biochemistry, Cellular and Molecular Biology (BCMB) graduate program at the Johns Hopkins University School of Medicine. He was elected to the National Academy of Sciences in 2005. He is a member of the American Society for Cell Biology, the American Society for Biochemistry and Molecular Biology, the Biophysical Society, and the American Association of Anatomists.

Contents
Biography

Research

Honors and Awards

References and External Links

Biography
Dr. Devreotes completed his undergraduate work in Physics at the University of Wisconsin–Madison in 1971. He received his Ph.D. degree in Biophysics from the Johns Hopkins University in 1977 where he performed his thesis research in the laboratory of Dr. Douglas Fambrough. He was a Damon Runyon Cancer Fund Postdoctoral Fellow with Dr. Theodore Steck at the University of Chicago from 1977 to 1980. Devreotes then moved back to the Johns Hopkins University where he rose from an Assistant and Associate Professor to Professor of Biological Chemistry from 1980 to 2000 and the Director of the Johns Hopkins Biochemistry and Molecular Biology (BCMB) Ph.D. Program from 1990 to 2000. He became Professor and Director of the Department of Cell Biology in 2000 and Isaac Morris and Elizabeth Hay Professor of Embryology in 2009.

A recognized international leader in his field, Devreotes is a member of the National Academy of Sciences. He has served on the Council of the American Society for Cell Biology, and the Advisory Boards of the Cell Migration Consortium and the Searle Scholars Program. He founded the Gordon Research Conference on "Gradient Sensing and Directed Cell Migration" and is on the Advisory Board of the Allen Institute for Cell Science. He is the author of more than 250 research articles, reviews and book chapters, and has trained over 70 pre- and postdoctoral fellows.

Research
Dr. Devreotes' research focuses on understanding how cells sense their surroundings and move towards chemical stimuli. Chemotaxis is critical for morphogenesis in development, immune cell trafficking, stem cell homing and wound healing, and it is exploited in disease states such as cancer metastasis. Dr. Devreotes was the first to identify chemoattractant receptors and to demonstrate that signaling events occur selectively at the cell's leading edge, studies that have led to the most definitive understanding of the strategy that cells use to sense direction. When Devreotes began his investigation of directed cell migration, the process was thought to occur only in bacteria and a few types of eukaryotes. His research has greatly advanced the understanding and appreciation of this fascinating process. Many of the concepts he discovered by developing Dictyostelium as a model system extend to cells throughout phylogeny, demonstrating the importance of this fundamental cell biological process in biology and medicine. Views have gradually been transformed by Devreotes through discoveries that signal transduction events in cells are local, a fact which is often overlooked in presentations in textbooks. Moreover, he has shown that signal transduction networks display biochemical excitability, a property that has profound implications for cell migration and cell morphology. This view has also led to a new understanding of how external cues influence the threshold for responsiveness, thereby directing migration.

Honors and Awards

 * Received the E.B. Wilson Medal from the American Society for Cell Biology (ASCB) (2019)
 * Elected as Inaugural Lifetime Fellow by the American Society for Cell Biology (ASCB) for distinguished contributions to the advancement of cell biology (2016)
 * Keynote Speaker, Gordon-Merck Research Seminar on Directed Cell Migration, Galveston (TX) (2013)
 * Keynote Speaker, Cold Spring Harbor Symposium on Axon Guidance, Cold Spring Harbor, NY (2010)
 * National Institutes of Health Merit Award "Signaling Networks in chemotaxis and cytokinesis" (2005)
 * Elected to the National Academy of Sciences (2005)
 * Elected to the rank of Council Member by the American Society for Cell Biology (ASCB) (2004)
 * American Heart Association Established Investigator (1984-1989)
 * American Cancer Society Junior Faculty Research Award (1981-1984)

References and External Links

 * Faculty Profile, Johns Hopkins University School of Medicine . Retrieved 2019-12-10.
 * Faculty Profile, BCMB Graduate Program, Johns Hopkins University School of Medicine . Retrieved 2019-12-10.
 * Secondary Faculty page, Department of Biological Chemistry, Johns Hopkins University School of Medicine . Retrieved 2019-12-10.
 * Johns Hopkins University Department of Cell Biology Welcome Page . Retrieved 2019-12-10.
 * Johns Hopkins University Department of Cell Biology Faculty Page . Retrieved 2019-12-10.
 * Johns Hopkins University, Devreotes Laboratory Website . Retrieved 2019-12-10.
 * Peter Devreotes named 2019 E. B. Wilson medalist . Retrieved 2020-03-27.
 * 2019 E.B. Wilson Medalist Peter Devreotes tells the story of chemotaxis . Retrieved 2019-12-10.
 * Johns Hopkins Cell Biologist Wins Professional Association’s Highest Honor . Retrieved 2020-03-27.
 * ASCB Elects 39 to Lifetime Achievement Fellows Program . Retrieved 2019-12-10.
 * Devreotes - Complete List of Publications . Retrieved 2019-12-10.
 * National Institutes of Health . Retrieved 2019-12-10.
 * The Allen Institute Advisor Profile . Retrieved 2019-12-10.
 * Nair, Prashant (2010). "QnAs with Peter N. Devreotes" . Retrieved 2019-12-10.
 * Program, Gordon-Merck Research Seminar on Directed Cell Migration 2013 . Retrieved 2019-12-11.
 * National Academy of Sciences, Member Directory, Peter Devreotes . Retrieved 2019-12-11.
 * Devreotes on ASCB Council Nominating Committee 2018 . Retrieved 2019-12-11.
 * Axon guidance, synaptic plasticity and regeneration meeting report, Cold Spring Harbor, NY (2010) . Retrieved 2019-12-17.
 * National Institutes of Health Merit Award, SIGNALING NETWORKS IN CHEMOTAXIS AND CYTOKINESIS, Devreotes, Peter N. . Retrieved 2019-12-19.