User:QTPie789/Xylulose 5-phosphate

Editing Xylulose-5-Phosphate stub article

Contribution 1:

In the non-oxidative branch of the pentose phosphate pathway, xylulose-5-phosphate acts as a donor of two-carbon ketone groups in transketolase reactions.

Article citation is: Stincone A, Prigione A, Cramer T, Wamelink MM, Campbell K, Cheung E, et al. (August 2015). "The return of metabolism: biochemistry and physiology of the pentose phosphate pathway". Biological Reviews of the Cambridge Philosophical Society. 90 (3): 927–963. doi:10.1111/brv.12140. PMC 4470864. PMID 25243985.

Contribution 2:

Xylulose-5-phosphate plays a crucial role in the regulation of glycolysis through its interaction with the bifunctional enzyme PFK2/FBPase2. Specifically, it activates protein phosphatase, which then dephosphorylates and inactivates the bifunctional enzyme. As a result, the production of fructose 2,6-bisphosphate increases, ultimately leading to an upregulation of glycolysis.

Article citation is: Uyeda K. (2021). Short- and Long-Term Adaptation to Altered Levels of Glucose: Fifty Years of Scientific Adventure. Annual review of biochemistry, 90, 31–55. https://doi.org/10.1146/annurev-biochem-070820-125228