User:Qtcells/sandbox

Norepinephrine is often used as a first-line treatment for hypotensive septic shock because evidence shows that there is a relative deficiency of vasopressin, when shock continues for 24 to 48 hours. In some patients, the required dose of vasopressor needed to increase the mean arterial pressure can become exceedingly high that it becomes toxic. In order to reduce the required dose of vasopressor, epinephrine may be added. Epinephrine is not often used as a first-line treatment for hypotensive shock because it reduces blood flow to the abdominal organs and increases lactate levels.

Dobutamine can also be used in hypotensive septic shock to increase cardiac output and correct blood flow to the tissues. Dobutamine is not used as often as epinephrine due to its associate side effects, which include reducing blood flow to the gut. Additionally, dobutamine increases the cardiac output by abnormally increasing the heart rate.

Comments
Thanks for sharing your proposed article improvements. I have a few small notes:

-On Wikipedia we refer to "people" rather than "patients" as per MEDMOS

-Please check and see if this is the first time technical terms and medical terms are used in Sepsis. On the first use, please add a Wikilink to help readers understand.

-Can you re-word your second second sentence to make it a little shorter? e.g.: "Some people with... require near-toxic doses of..." (this is just an example).

-You did a nice job adding references as per WP:MEDRS to each sentence.

If you have any questions please do not hesitate to let me know. I think your group is ready to improve the mainspace article!

Thanks again.

JenOttawa (talk) 8:50, 21 November 2018 (EST)