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Corneobiology refers to a cutaneous discipline centred on the structure and function of the stratum corneum. (Horny layer) It involves the biologic, biochemical and physiological aspects of this outer layer of the skin and is of particular importance in the understanding of the lines of skin barrier defense.

The science of Corneobiology encompasses numerous studies that deal with diverse topics such as immunology, endocrinology, neurobiology and psychology, and this is because the stratum corneum performs multiple functions from simple physical and permeability barrier functions, through antimicrobial activity to cytokine activation. (inflammation) The nature of these complex functions makes the stratum corneum of humans quite unique.

Prior to the mid 1960’s it was believed that the stratum corneum was an inert, passive membrane of dead cells, however subsequent studies conducted by eminent Corneobiologists Professor Albert Kligman, Professor Peter M Elias, Et Al showed the stratum corneum was very much alive; and in fact, a very complex, dynamic tissue whose formation involves many highly orchestrated metabolic enzymatic functions.

Today, the continuing study of Corneobiology provides valuable information that allows Dermatologists, Pharmacologists, Cosmetic Chemists and Corneotherapists to develop and provide effective, best practice solutions for a wide range of skin conditions.