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Pan Am Flight 202
Pan American World Airways Flight 202 was a Boeing 377 Stratocruiser aircraft that crashed in the Amazon Basin about 281 nmi southwest of Carolina, Brazil on April 29, 1952. The accident happened en route from Rio de Janeiro, Brazil, to Port of Spain, Trinidad, during the third leg of a four-leg journey. All 50 people on board were killed in the deadliest-ever accident involving the Boeing 377.

Newspaper Sources
http://memoria.bn.br/DocReader/DocReader.aspx?bib=348970_05&pagfis=12385