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Current Matters
However, two second generation antipsychotics (clozapine and asenapine), have demonstrated improvements for both the positive and negative symptoms of schizophrenia. A few SGAs have also demonstrated to yield cognitive improvements, such as improvements in verbal learning and memory, processing speed, and selective attention. Adjunctive antidepressant use with an atypical antipsychotic has also been demonstrated to be effective for improving the negative symptoms of schizophrenia, such as anhedonia, cognitive deficits, affective flattening, and avolition.

Saved References
1: Schizophrenia negative symptom improvement from atypical antipsychotics. 2: Adjunctive antidepressant use have demonstrated to improve the negative symptoms of schizophrenia. 3: Clozapine for positive and negative symptoms. 4: Negative symptom treatment with antipsychotics.