User:Rjcam2/Evaluate an Article

Which article are you evaluating?
P2RX4

Why you have chosen this article to evaluate?
I chose this article because part of my thesis work is understanding adaptations to the P2X4 receptor on microglia. These receptors are ionotropic and therefore also relates to the topic of biophysics. My preliminary impression of this article was poor. The content was vague and not up-to-date. The writing was unclear and the complete lack of figures adds to the obscurity.

Evaluate the article
Content: The writing is often vague or sporadically highly specific at times. No clear description of the receptor's function or structure is given: 'the P2X4 receptor has a typical P2X receptor structure." Some other details do not feel cohesive with the article such as comparing the desensitization rate with P2RX1 and P2XR2. There is some confusion whether the article's focus is about the receptor or at times the gene. Figure use is poor/nonexistent: no image of the receptor structure or cellular pathways regulating receptor trafficking although both are discussed. Only one section on neuropathic pain appears to have physiological application; however, the introduction mentions other types of cells expressing this receptor.

References: The first two references are the exact same link and do not work appropriately. Also, there is no in-text citation of these two. The most recent reference is from 2012 which is from a primary source (journal article). Another reference is from the NIH gene dataset; however, no access date from this source is presented. In other words, the information presented in the article using this citation is probably outdated, but no indication is given.

Talk page: There is only one comment on the talk page back from 2013 that states the editor restructured and expanded the content of the article. No further discussion is present.