User:Rmahoney4/sandbox

Physiology Article Notes: Endocrine Article:
 * Is each fact referenced with an appropriate, reliable reference?
 * The use of an online Etymology dictionary doesn't seem like a reliable reference for the definition of physiology.
 * Is everything in the article relevant to the article topic? Is there anything that distracted you?
 * I feel as though the women in physiology section was misplaced. I think it is fine to do a section like this but I think it should be a subsection of the history section instead of it's own.
 * Is the article neutral? Are there any claims, or frames, that appear heavily biased toward a particular position?
 * Article seemed to be pretty neutral to me. This may be because physiology is less of a subject that has to opposing sides and more of a fact based subject.
 * Where does the information come from? Are these neutral sources? If biased, is that bias noted?
 * Again the only problem I notice was the notion that the use of an online Etymology dictionary doesn't seem like a reliable reference for the definition of physiology.
 * Are there viewpoints that are overrepresented, or underrepresented?
 * "Much of the foundation of knowledge in human physiology was provided by animal experimentation." This sentence seemed to be a little bit out of place. Didn't really fit with the context of the ideas around it.
 * Check a few citations. Do the links work? Is there any close paraphrasing or plagiarism in the article?
 * In the final section of the article "Human Physiology" there is a big chunk of information that is not cited. Not sure where it came from.
 * Is any information out of date? Is anything missing that could be added?
 * How does the Wikipedia article compare to the ways we've discussed this topic in class? Does it align? What information might be incorrect or missing?

I just recently made an edit to the endocrine system article. I added an important notion about the h-h portal system between the anterior pituitary and the hypothalamus. I will be looking forward to making more edits to this article because there aren't many notions about the structures of the endocrine glands and how their structure contribute to their function.

Directly from article: I have bolded what I added.

"The pituitary gland (or hypophysis) is an endocrine gland about the size of a pea and weighing 0.5 grams (0.018 oz) in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain, and rests in a small, bony cavity (sella turcica) covered by a dural fold (diaphragma sellae). The pituitary is functionally connected to the hypothalamus by the median eminence via a small tube called the infundibular stem or pituitary stalk. .[citation needed] The anterior pituitary (adenohypophysis) is connected to the hypothalamus via the hypothalamo–hypophyseal portal vessels, which allows for quicker and more efficient communication between the hypothalamus and the pituitary."

For this addition I cited our physiology textbook from class. Vanders Human physiology.

I will also add to the disease section. I will include a section about hyper and hypothyroidism and hyper and hypocortisolism and specific diseases like addison's, cushings, graves, and gigantism diseases.

[null Clinical Endocrinology]. Jun2015, Vol. 82 Issue 6, p789-792. 4p. 2 Diagrams.

Buliman, A., Tataranu, L. G., Paun, D. L., Mirica, A., & Dumitrache, C. (2016). Cushing's disease: a multidisciplinary overview of the clinical features, diagnosis, and treatment. Journal Of Medicine & Life, 9(1), 12-18.

Inder, W. J., Meyer, C., & Hunt, P. J. (2015). Management of hypertension and heart failure in patients with Addison's disease. Clinical Endocrinology, 82(6), 789-792. doi:10.1111/cen.12592

Varadhan, L., Varughese, G. I., & Sankaranarayanan, S. (2016). Hyperthyroidism and Graves’ disease: Is an ultrasound examination needed?. Indian Journal Of Endocrinology & Metabolism, 20(6), 866-869. doi:10.4103/2230-8210.192899

Disease section (what I am adding)-

Other common diseases that result from endocrine dysfunction include Addison’s disease, Cushing’s disease and Grave’s disease. Cushing's disease and Addison's disease are pathologies involving the dysfunction of the adrenal gland. Dysfunction in the adrenal gland could be due to primary or secondary factors and can result in hypercortisolism or hypocortisolism. Cushing’s disease is characterized by the hypersecretion of the adrenocorticotropic hormone (ACTH) due to a pituitary adenoma that ultimately causes endogenous hypercortisolism by stimulating the adrenal glands. Some clinical signs of Cushing’s disease include obesity, moon face, and hirsutism. Addison's disease is an endocrine disease that results from hypocortisolism caused by adrenal gland insufficiency. Adrenal insufficiency is significant because it is correlated with decreased ability to maintain blood pressure and blood sugar, a defect that can prove to be fatal.

Graves' disease involves the hyperactivity of the thyroid gland which produces the T3 and T4 hormones. Graves' disease effects range from excess sweating, fatigue, heat intolerance and high blood pressure to swelling of the eyes that causes redness, puffiness and in rare cases reduced or double vision.