User:Robert M. Hunt



I'm an 82-year-old retired grandfather with a broad range of interests.

For 31 years I was a scientist at the University of Pennsylvania School of Medicine. My research included light and electron microscopic examination of bone and cartilage.

I chronicled for the first time in living tissue:

1. the critical role of chondrocyte mitochondrial calcium during the primary calcification of epiphyseal plate and bone fracture cartilage, and,

2. in a bone fracture, the progressive transformation of endothelial cells and pericytes into mesenchymal cells and their subsequent development into chondrocytes.

History of my family

 * William Bates (Quaker)
 * Joshua Evans (Quaker minister)
 * Alfred Hunt (steel magnate)
 * Elisha Hunt (steamboat pioneer)
 * Esther Hunt
 * Henry Thomas Hunt
 * John Hunt (Quaker minister)
 * John Hunt Painter
 * John Needles
 * Joseph Pancoast


 * Enterprise (1814)
 * Monongahela and Ohio Steam Boat Company
 * Mount Pleasant (Burlington County, New Jersey)

Other people and topics

 * Abner Lawson Duncan
 * John Fenwick (Quaker)
 * Daniel French (inventor)
 * Israel Gregg
 * John Randolph Grymes
 * John Hunt (Quaker exile)
 * Robert Hunt (chaplain)
 * Louis C. Hunter
 * Alexander A. Maximow
 * Barclay White
 * Canterbury (ship)
 * Comet (1813)

Significant contribution to a Wikipedia article initiated by another author

 * Samuel Leeds Allen
 * John Cadwalader (general)
 * John S. Collins
 * Edward Harris (ornithologist)
 * Lou Henry Hoover
 * Samuel K. Robbins
 * Dave Robinson (American football)
 * Robert H. Sayre
 * Henry Miller Shreve
 * Elizabeth Coleman White


 * Battle of New Orleans
 * Battle of Tientsin
 * Bone healing
 * Endochondral ossification
 * Intramembranous ossification
 * Mesenchymal stem cell
 * Mitochondrion
 * Moorestown High School
 * Moorestown Township
 * Osteoblast
 * Osteoclast
 * Paulsdale
 * Secrest Octagon Barn
 * Steamboats of the Mississippi

Selected publications

 * Brighton, Carl T., Yoichi Sugioka, and Robert M. Hunt (1973). "Cytoplasmic structures of epiphyseal plate chondrocytes; quantitative evaluation using electron micrographs of rat costochondral junctions with specific reference to the fate of hypertrophic cells". Journal of Bone and Joint Surgery, 55-A: 771-784.


 * Brighton, Carl T. and Robert M. Hunt (1974). "Mitochondrial calcium and its role in calcification". Clinical Orthopaedics and Related Research 100: 406-416.


 * Brighton, Carl T. and Robert M. Hunt (1978). "The role of mitochondria in growth plate calcification as demonstrated in a rachitic model". Journal of Bone and Joint Surgery, 60-A: 630-639.


 * Brighton, Carl T., Yoichi Sugioka, and Robert M. Hunt (1982). "Quantitative zonal analysis of cytoplasmic structures of growth-plate chondrocytes in vivo and in vitro". Journal of Bone and Joint Surgery, 64-A: 1336-1349.


 * Brighton, Carl T., Toshihiro Kitajima, and Robert M. Hunt (1984). "Zonal analysis of cytoplasmic components of articular cartilage chondrocytes". Arthritis and Rheumatism, 27: 1290-1299.


 * Brighton, Carl T. and Robert M. Hunt (1986). "Histochemical localization of calcium in the fracture callus with potassium pyroantimonate: possible role of chondrocyte mitochondrial calcium in callus calcification". Journal of Bone and Joint Surgery, 68-A (5): 703-715.


 * Brighton, Carl T. and Robert M. Hunt (1986). "Ultrastructure of electrically induced osteogenesis in the rabbit medullary canal". Journal of Orthopaedic Research 4: 27-36.


 * Brighton, Carl T. and Robert M. Hunt (1991). "Early histological and ultrastructural changes in medullary fracture callus". Journal of Bone and Joint Surgery, 73-A (6): 832-847.


 * Brighton, Carl T. and Robert M. Hunt (1997). "Early histologic and ultrastructural changes in microvessels of periosteal callus". Journal of Orthopaedic Trauma, 11 (4): 244-253.