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prosthetic Join infections

Prosthetic Joint Infection
A Prosthetic joint infection (PJI), involves a joint, such as a hip joint or knee joint, that’s been replaced, likely containing metal that’s become colonized with bacteria. The joint becomes symptomatic and generally results in swelling, pain and morbidity in patients, and in some cases, mortality. It is caused from either bacterium, such as staphylococcus aureus and pseudomonas aeruginosa, or a fungus. Where the infection occurs can vary from during the surgery, to the perioperative period, to much later seeding from another infection. If a patient has a cut on his foot that gets infected, it can certainly potentially seed an implanted joint. PJI is a major burden for healthcare systems. In addition to the significant morbidity and mortality associated with periprosthetic joint infection (PJI), the cost of treating PJI is substantial.

It is disabling for patients and may require invasive treatment with a risk of significant adverse events. The relative incidence of PJI ranged between 2.0% and 2.4% of total hip arthroplasties and total knee arthroplasties and increased over time. As the demand for joint arthroplasty is expected to increase substantially over the coming decade, so too will the economic burden of prosthetic infections.