User:SamTheBioGal/Angiotensin

Angiotensinogen
Angiotensinogen is synthesized in the liver and is a precursor for angiotensin, but has also been indicated as having many other roles not related to angiotensin peptides. It is a member of the serin family of proteins, leading to another name: Serin A8. In addition, a generalized crystal structure can be estimated by examining other proteins of the serin family, but angiotensinogen has an elongated N-terminus compared to other serin family proteins. Angiotensinogen is cleaved at the N-terminus by renin to result in angiotensin I, which will later be modified to become angiotensin II. This peptide is 485 amino acids long, and 10 N-terminus amino acids are cleaved when renin acts on it.