User:Samriddhi.M/sandbox

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Practice Editing Here (Nov 15th in-class Wiki session work)

 * This is a place to practice clicking the "edit" button and practice adding references (via the citation button).

Task:


 * 1) Find a peer-reviewed journal article on PubMed. Practice inserting your citation in the above space using the "cite" tool
 * 2) Choose one "B-level" medical article on Wikipedia from the following list: https://wp1.openzim.org/#/project/Medicine/articles?quality=B-Class&importance=High-Class
 * 3) Practice editing live on Wikipedia by finding a typo in the text or improving the clarity/readability of a sentence by adjusting a few words in a sentence.

Suggested change #12: Signs & Symptoms - Brain
Current sentence: Adding in addition to the currently written section.

Proposed change: It is important to note that neuropathic presentation can depend on etiological mutations underlying amyloidosis. People with amyloidosis may experience dysfunction in various organ systems depending on which nerves are impacted. For example, peripheral neuropathy can cause erectile dysfunction, incontinence and constipation, pupillary dysfunction, and sensory loss. In more serious cases, amyloidosis of the brain can cause life-threatening arrhythmias, cardiac failure, malnutrition, infection, or death.

Rationale for proposed change: The suggested additions will provide a more comprehensive understanding of the signs and symptoms of amyloidosis in the nervous system, specifically emphasizing the widespread, systemic impacts of amyloidosis neuropathy. The current “Brain” section does not do well in expanding upon the potential signs of symptoms of brain amyloidosis or acknowledge the peripheral impacts of neuropathy.

Area of controversy: To our knowledge, there is no controversy in our addition.

Critique of Source: The source is a secondary resource and narrative review. A possible source of bias could be publication bias, as there is limited research in brain amyloidosis. However, this source is a recently published review encompassing research on brain amyloidosis to date, therefore we do not foresee any issues with significant bias. While narrative reviews do not inform on statistical significance of results, this review was published in Seminars in Neurology, a trusted peer-reviewed journal with a 3.420 impact factor, indicating reliability in their conclusions.

What to post on the Wikipedia article talk page (part of assignment 3)

 * This will also be covered on Nov 15th in class. Your group should use the below template to share an outline of your proposed improvements (including your new wording and citations). Article talk pages are not places to share your assignment answers. The Wikipedia community will be more interested in viewing your exact article improvement suggestions including where you plan to improve the article (which section), what wording you suggest, and the exact citation (Note: all citations must meet WP:MEDRS)
 * You will not be able to paste citations directly from your sandbox to talk pages (unless you are interested in editing/learning Wiki-code in the "source editing" mode). We suggest re-adding your citations on the talk page manually (using the cite button and populating the citation by pasting in the DOI, website, or PMID). You will have to repeat this process yet again when you edit the actual article live.
 * Talk Page Template: CARL Medical Editing Initiative/Fall 2021/Talk Page Template

Wikipedia Article: Amyloidosis

Title: Oral amyloidosis: A strategy to differentiate systemic amyloidosis involving the oral cavity and localized amyloidosis