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Irene Frederic (C. C. H. Pounder) is a fictional character on the U.S. television science fiction series, Warehouse 13 (2009–present). she is more commonly known as, Mrs. Frederic, is the director and Caretaker of Warehouse 13. She is not the highest authority in regards to the Warehouse, however. She reports directly to The Regents, a mysterious group who oversee the Warehouse. Mrs. Frederic is also known for being a fearsome, stoic, and controlled figure. Although the Regents are the only people known to be on a first-name basis with her, she is fearfully known as Mrs. Frederic to all others.

Biography
It is hinted that for some reason she has not aged in a long time; she appears in a black and white photo and is stated to have worked in the Treasury Department in the 1950s, though Myka Bering believed the photo to be of someone else. When Pete and Myka time-traveled back to 1961 and inhabited the bodies of Jack Secord and Rebecca St. Clair, the senior agent of the time stated that Mrs. Frederic was reassigning them. In "Stand" it was mentioned that while the Warehouse is intact, the Caretaker cannot age.

Mrs. Frederic is the current Caretaker of Warehouse 13 and as such is connected symbiotically to the Warehouse. The Warehouse seems to have some effect on Mrs. Frederic, the extent of which is unknown. In the episode Buried she shows extensive knowledge of the history of the Warehouse and appears to show a temporary capability to explore inventory of Warehouse 2 at will by focusing her mind.

In the episode Stand, she dies in front of Claudia Donovan and Leena due to the Warehouse's destruction. Oddly, her body seemed to decay a lot faster than normal.

In A New Hope, though the use of the astrolabe, Artie was able to bring back both Mrs. Fredrick and H.G. Wells. Mrs. Fredrick spoke to Artie and asked what he did, noting that part of her hair has gone grey.

In No Pain, No Gain, It is revealed that her son, mentioned in Shadows, is long dead, and her elderly grandson is in a retirement home.

In 13.1, Douglas Fargo calls her: "The scary lady with the beehive."

Skills and abilities
As the Caretaker, some sort of mental link exists between her and the Warehouse, giving her, among other advantages, a full mental inventory of all artifacts in Warehouse 13. Another result of this is that her life and the Warehouse's life are linked; if one dies, both die. As such, she is immune to natural death, resulting in her appearance never changing in spite of her advanced age. In the "Pilot" episode, Dickinson's research uncovers that she worked for the Treasury Department in the 1950s. It is revealed in the season 2 episode "Where and When" that she has been in charge at the Warehouse since at least 1961.

She is also in tune with her aura and experiences "vibes" in the same way that Agent Lattimer does. Mrs. Frederic is also known for being a shadowy figure that suddenly appears and disappears. It is also theorized that Ms. Frederic can teleport because several times she has inexplicably appeared and disappeared when no one was looking. How exactly she achieves this is still unknown. The act is commonly called “Pulling a Mrs. Frederic” by the warehouse agents whenever someone seemingly appears out of thin air.

In No Pain, No Gain, It is revealed that she has the ability to predict the birth of an artifact before it happens, a skill she teaches Claudia.