User:Sasahad/Alkaline phosphatase/WKB321 Peer Review

General info
Sasahad
 * Whose work are you reviewing?


 * Link to draft you're reviewing:Alkaline phosphatase - Wikipedia
 * Link to the current version of the article (if it exists):

Evaluate the drafted changes
(Compose a detailed peer review here, considering each of the key aspects listed above if it is relevant. Consider the guiding questions, and check out the examples of what feedback looks like.)

The lead section is quite strong.What I think it lacks is some information about the structure of the enzyme, as well as the mechanisms it uses to function. You said that the enzyme functions by dephosphorylating compounds and that it plays an integral role in metabolism. It isn’t clear to me how the two are related. You stated that the enzyme plays an “integral role” but didn’t make it clear how exactly it functions in the body. I think this information should replace information about the measuring processes of the level of AP in the body. While this information is useful, it doesn’t tell us anything about the enzyme itself and thus shouldn’t take up a large portion of the lead, if any.

Some sentences feel very wordy. The article makes several claims regarding the unusual characteristics of AP enzymes. Some of the claims didn’t have strong evidence stated. It is also unclear which characteristics make up a “normal” enzyme.

The article makes several medical claims, relating AP enzymes and certain conditions/diseases. Anything related to medical conditions is treated much more seriously on wikipedia than anything else. That is, it is checked for credibility more heavily and needs to have appropriate sources. People who are not licensed medical providers should avoid adding such information, if possible, or provide extensive sources/evidence.

Overall, the structure of the article is good. However, I would strongly recommend putting the section "Structure and properties" at the beginning of the article, since it describes the enzyme's properties, which is the most important part of the article.

I didn’t sense any bias in the article. All of the information presented seemed to have a neutral tone.

The links work, and most of the information presented has appropriate links.

The weakest point of the article is not having enough information on the chemistry behind the function of the enzyme. I would include more information about the structure of it in the beginning. I think it would be useful to explain in the beginning what exactly about the enzyme makes it heat stable, or why it functions best in alkaline conditions, in contrast with other enzymes. You could also include information about its mechanism, or how exactly it takes off a phosphate group. Having reviewed the article, I realized that this is my weakest point too.

Overall, it is clear that extensive research went into the creation of the article, and that a wide variety of sources were used to illustrate the AP enzyme from a variety of perspectives.

~WKB321