User:Savani1987/sandbox

Barrier
In multi-cellular organisms, a barrier is structural entity between neighboring cells. Examples of barrier are blood–air barrier, Blood–brain barrier, Gastric mucosal barrier, Blood–testis barrier, Blood–ocular barrier, Blood–retinal barrier.

Structure
Generally, barrier consist of tight junctions.

Function
Barrier serves to prevent unregulated intercellular exchange of molecules.

Factors affecting barrier
Mutations affect barrier proteins leads to dysfunctional barrier.

Other barrier disruptors include
 * phosgene, Cadmium chloride,
 * Bacterial toxin's : Hemolysin from Staphylococcus aureus and
 * Spider venom: Brazilian wandering spider.

Diseases
Barrier dysfunction is related to numerous diseased conditions.