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Australasian Physical & Engineering Sciences in Medicine (APESM) is a quarterly peer reviewed scientific journal covering research on medical physics and biomedical engineering, particularly within Australasia. APESM is the official journal of the Australasian College of Physical Scientists and Engineers in Medicine (ACPSEM).

The journal was first published in 1977 as Australasian Physical Sciences in Medicine, having since changed its name in 1980. It has been published by Springer Publishing since 2001. The journal replaced the earlier Australasian Bulletin of Medical Physics and Australasian Newsletter of Medical Physics, which was first distributed in December 1959.

The Kenneth Clarke Journal Prize is awarded annually for the best paper published in the journal in the previous year.

Abstracting and indexing
APESM is indexed in:
 * Index Medicus/MEDLINE/Pubmed
 * Scopus

It has a 2014 impact factor of 0.882, according to the Journal Citation Reports.