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Cayman Chemical Company is a biochemical products manufacturing and research company with headquarters in Ann Arbor, Michigan.

Incorporated on June 6, 1980 in Denver, Colorado, Cayman Chemical Company was initially a marine natural products company. Building on earlier environmental studies in the North Sound of Grand Cayman Island, Cayman initially sold prostaglandin standards as research chemicals.

Commercializing the patented work of Philippe Pradelles and others, Cayman exploited the acetylcholinesterase enzyme of electric eels to develop a wide range of sensitive enzyme immunoassays for prostaglandins in the late 1980s.

The availability of these assays also enabled the development of Celebrex by Searle/Monsanto, relying on measurements of Prostaglandin E2 and Thromboxane B2, and of Singulaire by Merck, relying on measurements of unstable Leukotrienes.