User:Seanmcaruthers/sandbox

Pillar 1

 * Wikipedia is an encyclopedia - Just the facts ma'am. Wikipedia is a logically organized set of entries intended to cover all branches


 * of knowledge. In this regard, Wikipedia must contain only verifiable material and cannot be used to promote any single viewpoint.

Pillar 2

 * Wikipedia is written from a neutral point of view - Wikipedia uses the platform to express informative and verifiable information on


 * its topics. While many topics may be controversial(and the most searched for often are), the topic can be covered in a neutral and


 * unbiased manner. Facts, history, laws of nature, etc., while at times poorly understood, are fixed.  A topic must be covered with all


 * pertinent viewpoints represented, with intentional or unintentional distortions.

Pillar 3

 * Wikipedia is free content that anyone can edit, use, modify, and distribute - All posts to Wikipedia are public property. Ownership,


 * copyright, exclusivity, etc. do not exist for the edited pages of Wikipedia. While discouraged, non-free content may be used.


 * Plagiarism is not tolerated. Your entries and edits can and will be carved up in order to make Wikipedia the best it can be.

Pillar 4

 * Editors should treat each other with respect and civility - Do onto other editors as you would do unto your own edits. Most Wikipedia
 * editors(except the trolls, vandals, those with agendas, etc.) are here to make the information as broad and reliable as possible. We
 * are all on the same team.

Pillar 5

 * Wikipedia does not have firm rules - Wikipedia is open. Its strength is based on the dedication of editors to present each topic


 * truthfully, reliably and unbiased.

==Summary of characteristics of target article ==
 * An article that reaches our desired quality level will accomplish the following goals


 * Complete
 * Useful to all readers
 * Fully referenced to original sources
 * Our article should not have major style, design or flow problems.

=Citation practice= The article "The impact of transposable elements on eukaryotic genomes: from genome size increase to genetic adaptation to stressful environments" is a recent review on transposable elements and their impact on genome structure. The authors pay particular attention to the role of stress in transposon activation and effects on evolution. The authors discuss the historical progression of transposon research, from Barbara McClintock's Nobel prize winning work in the discovery of transposons to current work based on the ability to generate massive amounts of sequence data. McClintock's original paper is cited 108 times in PMC. Of particular interest to me was the article "Transposon activation mutagenesis as a screening tool for identifying resistance to cancer therapeutics." Here, Chen et al. describe their work using engineered transposons to mutagenize cancerous cell lines and discovery of drug resistance genes by sequencing of resistant cell lines.