User:Sereineke/sandbox

ADD TO EARLY LIFE

At age 13, her mother died and her father worked three jobs to help support her educational ambitions.

ADD TO CAREER

While in China, she studied different diseases found in citrus fruits and beans. Yu became a U.S. citizen in the 1950s. She became an associate professor of internal medicine.

Dr. Tsai-Fan Yu also helped to found a clinic at Mount Sinai to aid in the treatment of gout. She worked alongside Alexander B. Gutman at the clinic for much of her research on gout. Yu began studying renal function in various diseases such as Wilson's disease before focusing her research on gout at Mount Sinai. She also aimed to classify and determine the differences the various forms of gout, such as acute gouty arthritis and chronic tophaceuous gout.

In 1953, Dr. Tsai-Fan Yu conducted research on phenylbutazone as a treatment for various arthritic disorders, one being acute gouty arthritis. She and colleagues found that phenylbutazone injection lead to significantly higher urate clearance and more efficient excretion, making it successful in treating acute gout. In 1980, she studied carprofen and its effect on urinary excretion. She found it was effective for treating acute gouty arthritis and recommended futher trials.

She also studied the effect that other medication conditions have on the presentation of gout. She found that about half of the patients with gout have associated medication conditions, including hypertension, proteinuria, diabetes, and hyperlipidemia.

--Awards and Honors --

She also was the co-author and publisher of the book, Gout and Acid Metabolism, in 1976.

Over the course of her career, she worked with over 4000 gout patients at one of the largest gout-focused practices. She also published 220 scientific journal articles and is known for her ability to translate lab research into an effective treatment for patients. She is aunt to Hua Eleanor Yu, a professor in tumor immunotherapy and Humboldt Research Award recipient.