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Hudson, Lester et al. tested whether a ‘risk index’ combining demographic (age, gender); clinical (primary anxiety disorder severity, presence of comorbid mood and externalizing disorders) and genetic factors (5HTTLPR and NGF rs6330 polymorphisms) predicted non-remission following CBT in children with a primary anxiety disorder. Children obtaining high scores on this risk index were approximately three times as likely to retain their anxiety disorder at a follow up assessment. This research represents an initial attempt to use therapygenetics data in a clinically informative way.