User:Shahendak/sandbox

Deoxyuridine Compound
Deoxyuridine is a compound and a nucleoside. It belongs to a class of compounds known as Pyrimidine 2'-deoxyribonucleosides and closely resembles the chemical composition of uridine but without the presence of the 2' hydroxyl group. This compound exists in all living organisms and can become part of DNA in both prokaryotic and eukaryotic cells through two mechanisms. The first is the removal of an amino group from cytosine to result in uracil and the second is the non-intentional incorporation of pyrimidine where thymine belongs in the DNA, resulting in dUMP. Ump synthase deficiency is a metabolic disorder in humans that involves deoxyuridine. Deoxyuridine can be a toxic compound. It has also been found outside the body in several food, which makes it a useful indicator for diseases through consumption of those foods.

http://www.hmdb.ca/metabolites/HMDB0000012

https://www.ncbi.nlm.nih.gov/pubmed/6147963

http://www.ymdb.ca/compounds/YMDB00221