User:Shea46/sandbox

Welcome to your sandbox!

Link to Project Resource Page
Project Homepage and Resources

Practice Editing Here (Nov 23rd in-class Wiki session work)

 * This is a place to practice clicking the "edit" button and practice adding references (via the citation button).
 * My Wiki article is titled Chronic Lymphocytic Leukemia (Chronic lymphocytic leukemia).

Assignment # 3
Original sentences:
 * Note: You will be emailing your assignment # 3 directly to your tutor, however, please paste a version here that excludes your personal information. This will allow us to support your efforts on Wikipedia prior to editing "live" in the article.

Management of early disease is generally with watchful waiting. Infections should more readily be treated with antibiotics.

Proposed changes :

Early-stage CLL in asymptomatic cases responds better to careful observation, as there is no evidence that early intervention treatment can alter the course of the disease. Immune defects occur early in the course of CLL and these increase the risk of developing serious infection, which should be treated appropriately with antibiotics.

Rationale :

Sentence 1: The original sentence is vague and doesn’t explain why ‘watchful waiting’ is recommended for early-stage CLL. The review article by Stilgenbauer et al. confirms that early intervention has not been shown to be effective. The modifications I have made expand on the content originally stated. The new sentence explains that early-stage CLL responds better with careful long-term monitoring, rather than aggressive treatment. There is no ambiguity with this statement as it has been confirmed by the International Workshop on CLL’s (IWCLL) standardized guidelines and is supported by evidence-based research.

Sentence 2: The original sentence seemed out of place as it didn’t relate to the previous sentence. For someone with little knowledge on the topic, this sentence could be misunderstood as it is unclear which infections they are referring to. The review article by Stilgenbauer et al. presents infections as one of the most common complications of CLL. The new sentence emphasizes that although no treatment is recommended in early-stage CLL, long-term monitoring is especially important to prevent any serious complications. There is also no ambiguity with this statement as it is well-known that CLL increases the risk of serious infection and should be treated with antibiotics.

Critique of Source :

The source I selected was published in 2015, which as per Wikipedia’s guidelines is considered current. However, a lot can change in five years of research and the findings presented in the journal could be outdated. I still decided to use this resource, even though there were more recent articles because it expanded upon the most recent set of standardized criteria for the treatment of CLL. In addition, this review article is peer-reviewed and was published in a reliable and authoritative journal, the American Journal of Clinical Oncology. The information presented in the article is relevant and comprehensive. Furthermore, this review article had no reported conflicts of interest compared to other more recent sources I considered. No other biases are observed.

What to post on the Wikipedia article talk page?

 * This will also be covered on Nov 23rd in class. Your group should use the below template to share an outline of your proposed improvements (including your new wording and citations). Article talk pages are not places to share your assignment answers. The Wikipedia community will be more interested in viewing your exact article improvement suggestions including where you plan to improve the article (which section), what wording you suggest, and the exact citation (Note: all citations must meet WP:MEDRS)
 * You will not be able to paste citations directly from your sandbox to talk pages (unless you are interested in editing/learning Wiki-code in the "source editing" mode). We suggest re-adding your citations on the talk page manually (using the cite button and populating the citation by pasting in the DOI, website, or PMID). You will have to repeat this process yet again when you edit the actual article live.
 * Talk Page Template: CARL Medical Editing Initiative/Fall 2020/Talk Page Template