User:Sminthopsis84/Meiome

Meiome is the term used in functional genomics for meiotic transcriptome. Meiosis is a key feature for all sexual reproducing eukaryotes in which homologous chromosome pairing, synapse and recombination are unique. Since meiosis in most organisms occur in a short time period, study of meiotic transcript profiling is extremely hard due to the challenge of isolation of meiotic cells. There are a list of groups studying on meiotic transcriptome using high throughput techniques such as microarray and sequencing technologies.

Meiome is the way to study transcript profiling using mRNA isolated from enriched meiotic cells (meiocytes). Currently there are two major approaches to understand the RNA accumulation in meiocytes: 1) RNA-seq and 2) Microarray. The RNA-seq tech is more powerful for whole transcriptome analysis, the available analyzers such as Illumina Genome Analyzer 2 and Roche 454 analyzer made this approach more powerful.