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Isabelle Mansuy is Professor in Neuroepigenetics at the Medical Faculty of the University Zürich (UZH), and the Department of Health Science and Technology of the Swiss Federal Institute of Technology Zürich (ETHZ). She is known for her work on the heritability of trauma.

Education
Mansuy studied Molecular Biology and Biotechnology in the Ecole Supérieure de Biotechnologie de Strasbourg (ESBS), the first international engineer school teaching genetic engineering at the time. After graduating, I. Mansuy completed a PhD at the Friedrich Miescher Institute in Basel then a postdoc at Columbia University in New York where she gained expertise in neurobiology and in the design and use of transgenic mouse models. She established a lab as an assistant professor at the ETH Zürich at the end of 1998 and a few years later became full professor in Neuroepigenetics at the University Zürich and ETHZ.

Research
Isabelle Mansuy`s research examines the epigenetic basis of complex brain functions and physiology in mammals and focuses in particular, on the mechanisms of epigenetic inheritance. The goal is to determine the molecular and cellular processes underlying the influence of life experiences on mental and physical health across generations. Her research focuses on adverse experiences in early life and their link with psychiatric and metabolic disorders. It uses animal models and cellular systems to study the involvement of non-coding RNAs, epigenetic factors and chromatin remodeling in the brain and germline, in the expression and transmission of environmentally-induced phenotypes. The work demonstrated that early adversity in mice induces behavioural and metabolic alterations that are transmitted across up to 4 generations through the germline and is currently working on identifying the causative factors.

Awards

 * 2017 Elected member of the European Academy of Sciences (EURASC)
 * 2016 Knight in the Order of the Legion of Honor, France
 * 2011 Elected member of the Research Council of the Swiss National Science Foundation
 * 2011 Knight in the Order of Merit, France
 * 2010 Elected member of the Swiss Academy of Medical Sciences
 * 2008 Robert Bing Prize
 * 2006 EMBO member
 * 2004 FEBS Anniversary Award
 * 2004 Boehringer Ingelheim FENS Research Award
 * 2001 EMBO Young Investigator Program Award
 * 1997 Fyssen Foundation Research Award

Articles

 * https://www.media.uzh.ch/en/Press-Releases/archive/2016/reversal-of-trauma.html


 * https://www.hifo.uzh.ch/dam/jcr:7a7198c0-7b3e-4147-ae06-93304b7efdee/Science%20Magazine%20-%20212.full.pdf
 * Article on Isabelle Mansuy`s research in Sonntagszeitung

Radio & TV

 * Radio broadcast at RJB "Et si certains traumatismes modifiaient nos gènes?"
 * TV broadcast at Indus News "Mind over State"

Book
Reprenez le contrôle de vos gènes (Take control of your genes) ISBN 978-2-03-595621-7