User:Sophiereid98/sandbox

Discovery
Each DAZ protein family member was discovered individually, over a period of time by different research groups. BOULE was first identified in Drosophila, with homologs being found in other organisms, from sea anemone to humans, DAZL is thought to have come from BOULE by a gene duplication event and was first discovered in mice, but is present in all vertebrates, and the Y-chromosomal DAZ gene was first found in infertile males, but is also present in apes and Old World monkeys. DAZ arose during primate evolution by (i) transposition (moving) from the autosomal gene to the Y chromosome, (ii) removing unwanted parts of exons within the transposed gene and (iii) amplification (making multiple copies) of the modified gene.