User:Stellur/Uniporter/Bibliography

You will be compiling your bibliography and creating an outline of the changes you will make in this sandbox.

Outline of proposed changes
Click on the edit button to draft your outline. I. Introduction to Uniporters (Lead section)

- Revise incorrect information on function of uniporters

- Uniporters are not ion channels (they are different)

- Each sentence requires in-line citation

- Include information on the different types of uniporters

A. Definition and Function

B. Comparison with Active Transport

C. Categories: Channels and Carriers

'''II. Mechanisms and Regulation of Uniporters'''

- Add a new subsection that specifically talks about the mechanism of facilitated diffussion in uniporters

- Uniporters conformational change when binding a protein

A. Facilitated Diffusion: Uniport, Symport, Antiport

B. Regulation Factors:

1. Voltage

2. Stress

3. Ligand

'''III. Localization and Functions of Uniporters'''

- Add a new section that describes the different types of uniporters

A. Mitochondrial Calcium Uniporter (MCU)

B. Glucose Transporters (GLUTs)

C. Large Neutral Amino Acid Transporter (LAT1)

D. Equilibrative Nucleoside Transporters (ENTs)

'''IV. Discovery of Uniporters'''

A. Early Research on Osmosis and Diffusion

B. Role of Fick's Laws of Diffusion

C. Facilitated Diffusion Discovery

D. Studies on Glucose and Nutrient Transport

E. Advancements in Biochemistry and Genetic Studies

V. Mechanism of Uniporters

A. Three-dimensional Shape Changes

B. Translocation Across Membranes

C. Differentiation from Symporters and Antiporters

'''VI. Importance and Physiological Roles of Uniporters'''

A. Nutrient Uptake

B. Ion Homeostasis

C. Metabolism and Energy Production

D. Cell Signaling and Communication

E. Waste Removal and pH Regulation

'''VII. Mutations in Uniporters and Associated Diseases'''

A. GLUT1 Deficiency Syndrome

B. Cystic Fibrosis

C. Hypokalemic Periodic Paralysis

D. Hartnup Disease

E. Primary Hyperoxaluria

'''VIII. Future Directions and Research Areas'''

A. Recombinant DNA Technology and Electrophysiology

B. Structural Studies and Real-time Imaging

C. Implications for Disease Treatments and Diagnostics

'''IX. Conclusion: Uniporters' Essential Role in Cellular Function'''