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= Pearl E. Grimes, MD, FAAD =

Early Life and Education
Pearl E. Grimes was born into a family of six in Woodville, Mississippi to professor Ephraim M. Grimes and Ruby Dillon Grimes. Raised in a household that encouraged "resilience, compassion, and the spirit of giving," Grimes later creates a foundation supporting at-risk youth, CARRY, and does numerous studies on multiple skin diseases. She went to Jackson State University in Jackson, Mississippi and graduated in 1970 with a Bachelor of Science in Biology with Magna Cum Laude. Dr. Grimes received her M.D. from Washington University in St. Louis in 1974 and completed her residency in dermatology at Howard University Hospital.

Career
Pearl E. Grimes MD is a highly experienced Dermatologist with over forty years of experience. After completing her residency at Howard University in Washington, D.C., Dr. Grimes was accepted a position as an assistant Professor in the University's Department of Dermatology (Jul 1980 – Jan 1984). During this time she also served as a Medical Director for the School's Vitiligo Research Center where she continued to gain an understanding in pigmentation disorders (Dec 1979 – Jan 1984). In the spring of 1984 Dr. Grimes moved to California where she founded and became the Medical Director of the Vitiligo & Pigmentation Institute Of Southern California (1990 – Present).

As the Medical Director of the Vitiligo and Pigmentation Institute of Southern California, Dr. Grimes has patients who travel from all over the world for her expertise in a variety of health and aesthetic Dermatological concerns. Services she offers include but aren't limited to: Acne treatment, Vitiligo treatment, BOTOX, Alopecia treatment, and Psoriasis treatment.The Vitiligo & Pigmentation Institute Of Southern California has performed and continues to perform a number of Clinical research trials for a variety of skin and hair disorders. Some of her notable past studies include: FDA approval of Botox, Juvaderm, and Tazorac. Dr. Grimes was a pioneer in Botox research and published the first paper on botox use in African Americans.

In California Dr. Grimes also worked for UCLA, she worked as an Assistant Professor of Dermatology for over a decade (Mar 1984 – 1994). She then served as an associate professor of Dermatology until she eventually rose to hold the position of Clinical Professor of Dermatology where she gave lectures and provided practical guidance and instruction to professional students (Feb 2005 – 2016). Despite no longer affiliated with UCLA in a teaching capacity, Dr.Grimes continues to give lectures globally especially focusing on pigmentation disorders.

CARRY
In 2006, Dr. Grimes founded the Coalition for At-Risk-Restoring Youth (CARRY). CARRY is a nonprofit dedicated to youth who are considered at risk or who in currently in foster care. The CARRY website states their mission statement as: “[making] a difference in the lives of foster-care and at-risk youth by providing programs that enhance self-esteem, self-worth, self-sufficiency, and long term success.” There are numerous programs children can participate in through CARRY, the first program was one that focused on dermatology but they have since expanded and now offer camps to teach self esteem and social skills and etiquette. They also run a musical theater and performing arts camp.CARRY has provided more than $150,000 in pro bono services to more than 4,000 youth each year since it was established.

Board Memberships

 * American society of dermatology


 * American Society of Dermatologic Surgery
 * American Dermatological Association
 * Society of Investigative Dermatology
 * Dermatology Foundation
 * International Pigment Cell Society
 * Women’s Dermatologic Society (President, 2017-2018)

Awards
Dr. Pearl Grimes has received many awards in recognition of her contributions to the field of dermatology. Her awards include: the 2019 Alan Shalita Memorial Award, the 2017 Lifetime Achievement in Dermatology Award from the American Skin Association, the 2017 Everett C. Fox Memorial Award and Lectureship from the American Academy of Dermatology, the 2017 Goldman Humanitarian Award from the American Academy of Dermatology, 2017 Women’s Dermatologic Society Legacy Award, the 2011 Women’s Dermatologic Society Mentor of the Year Award, the 2011 Dermatology Foundation Practitioner of the Year, as well as longstanding inclusion on lists such as Los Angeles Magazine Super Doctor, Best Doctors of America and the Hollywood Reporter’s Top Hollywood Doctors.

== Publications == Dr. Grimes has published numerous studies since the start of her career. Most of her studies focus on understanding and safely combating pigmentation disorders in all ethnicities and skin types.


 * A double-blind, randomized, multicenter, controlled trial of suspended polymethylmethacrylate microspheres for the correction of atrophic facial acne scars.
 * Karnik, J.,Baumann, L.,Bruce, S.,Callender, V.,Cohen, S.,Grimes, P.,Joseph, J.,Shamban, A.,Spencer, J.,Tedaldi, R.,Werschler, W. P.,Smith, S. R.
 * An efficacy study of 3 commercially available hydroquinone 4% treatments for melasma.
 * Grimes, P. E.


 * Management of hyperpigmentation in darker racial ethnic groups.
 * Grimes, P. E.
 * Polymethylmethacrylate Collagen Gel-Injectable Dermal Filler for Full Face Atrophic Acne Scar Correction.
 * Joseph, J. H.,Shamban, A.,Eaton, L.,Lehman, A.,Cohen, S.,Spencer, J.,Bruce, S.,Grimes, P.,Tedaldi, R.,Callender, V.,Werschler, P.
 * Comparison of 311-nm Titanium:Sapphire laser and 308-nm excimer laser treatment for vitiligo: A randomized controlled non-inferiority trial.
 * Bae, J. M.,Eun, S. H.,Lee, H. N.,Kim, G. M.,Grimes, P. E.,Lee, J. H.
 * International Initiative for outcomes (INFO) for vitiligo: Workshops with vitiligo patients on repigmentation.
 * Eleftheriadou, V.,Hamzavi, I.,Pandya, A.,Grimes, P.,Harris, J. E.,Huggins, R. H.,Lim, H. W.,Elbuluk, N.,Tovar-Garza, A.,Nahhas, A. F.,Braunberger, T.,Ezzedine, K.
 * Safety and Effectiveness of the Hyaluronic Acid Dermal Filler VYC-17.5L for Nasolabial Folds: Results of a Randomized, Controlled Study.
 * Monheit, G.,Beer, K.,Hardas, B.,Grimes, P. E.,Weichman, B. M.,Lin, V.,Murphy, D. K.
 * Updates in the understanding and treatments of skin and hair disorders in women of color.
 * Grimes, P. E.
 * Indications and limitations of afamelanotide for treating vitiligo-reply.
 * Lim, H. W., Grimes, P. E., Lebwohl, M.
 * A multicenter study of the safety and effectiveness of hyaluronic acid with a cohesive polydensified matrix for treatment of nasolabial folds in subjects with Fitzpatrick skin types IV, V, and VI.
 * Downie, J. B., Grimes, P. E., Callender, V. D.
 * Treating epidermal melasma with a 4% hydroquinone skin care system plus tretinoin cream 0.025%.
 * Grimes, P., Watson, J.
 * Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method.
 * Pandya, A. G., Hynan, L. S., Bhore, R., Riley, F. C., Guevara, I. L., Grimes, P. E., Nordlund, J. J., Rendon, M. I., Taylor, S. C., Gottschalk, R. W., Agim, N. G., Ortonne, J.