User:Stetso/New sandbox

Proposition for Article:

Epigenetics and Sleep: -The role of epigenetics in the development of sleep disorders, stress-related impacts on sleep, and the long-term impact of certain sleep habits -sleep deprivation causes significant epigenetic changes -there is hope for epigenetic-centered therapy to become a successful form of treatment for sleep disorders, considering epigenetic modifications associated with the disorders themselves -decreased methylation of differentially methylated positions has been correlated with the genetics of individuals who do not get enough sleep (hypomethylation on chromosome 17 is especially significant) -treating the modulation of dopaminergic signals may serve as a way to decrease lucid nightmares in individuals suffering from PTSD -sleep is a particularly interesting topic to study in relation to epigenetics because epigenetic modifications alter the experience while how one sleeps leads to additional epigenetic modifications

-Potential Figures to be created: --epigenetic mechanism of the effects of sleep deprivation --epigenetic treatment of lucid nightmares (dopaminergic pathways) --epigenetic abnormalities linked to sleep disorders

References: Blum, K., McLaughlin, T., Modestino, E. J., Baron, D., Bowirrat, A., Brewer, R., Steinberg, B., Roy, A. K., Febo, M., Badgaiyan, R. D., & Gold, M. S. (2021). Epigenetic Repair of Terrifying Lucid Dreams by Enhanced Brain Reward Functional Connectivity and Induction of Dopaminergic Homeostatic Signaling. Current psychopharmacology, 10, 10.2174/2211556010666210215153513. https://doi.org/10.2174/2211556010666210215153513

Cortese, R. (2021). Epigenetics of Sleep Disorders: An Emerging Field in Diagnosis and Therapeutics. Diagnostics, 11(5), 851. MDPI AG. Retrieved from http://dx.doi.org/10.3390/diagnostics11050851

Abandoned Idea: The Epigenetics of Bipolar Disorder