User:Stuartmacg

About me
Hello! My name is Stuart MacGowan, and I am a computational biologist specializing in protein structural bioinformatics. I hold a PhD in Chemistry and a BSc (Hons) in Chemistry and Mathematics. I am currently affiliated with the University of Dundee, where I conduct research on various aspects of computational biology.

Research
I have been involved in several research projects and publications, including studies on the effects of missense mutations in SARS-CoV-2 Spike and human ACE2 interaction. Some of my notable publications are:


 * MacGowan, S.A., Barton, M.I., Kutuzov, M., Dushek, O., van der Merwe, P.A., et al. (2022). Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants. PLOS Computational Biology, 18(3), e1009922. https://doi.org/10.1371/journal.pcbi.1009922
 * Barton, M.I., MacGowan, S.A., Kutuzov, M.A., Dushek, O., Barton, G.J., & van der Merwe, P.A. (2021). Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics. eLife, 10, e70658. https://doi.org/10.7554/eLife.70658

Contributions to Wikipedia
I contribute to Wikipedia by sharing my expertise in protein structural bioinformatics and improving related articles. I am committed to maintaining a neutral point of view, ensuring accuracy, and providing well-referenced information. If you have any questions or suggestions regarding my contributions, feel free to leave a message on my talk page.

Disclaimer
I strive to avoid conflicts of interest in my contributions to Wikipedia. If you believe any of my edits appear biased or promotional, please bring it to my attention on my talk page, and I will do my best to address the issue.