User:Studentdoc2022/Bungarotoxin/Fauci2.0 Peer Review

General info

 * Whose work are you reviewing?

Studentdoc2022


 * Link to draft you're reviewing?
 * https://en.wikipedia.org/wiki/User:Studentdoc2022/Bungarotoxin?veaction=edit&preload=Template%3ADashboard.wikiedu.org_draft_template
 * Link to the current version of the article (if it exists)
 * Bungarotoxin

Evaluate the drafted changes
Lead

-I would add a brief introductory lead summarizing the main points of Bungarotoxins

Content

-Overall good content and flow.

-History section is nice, I have no suggestions

- Snake bite section: I would recommend expanding on the epidemiology to include snake bites as they relate to bungarotoxins. Maybe you can find a source that gives an estimate of snake bite encounters from the Krait family of snakes and talk about the approximate morbidity and mortality associated with this toxin. I was reading elsewhere that the primary cause of death related to bungarotoxins is that they cause respiratory failure and in low-resource settings there is often a lack of ventilatory support, which increases mortality.

-Toxin mechanism: I would add a sentence at the beginning of the section that describes the mechanism in layman's terms. For instance, maybe it would go something like this "Bungarotoxins cause paralysis by blocking the transmission of signals in nerves and muscles". Then you could go into the specifics for each type of toxin. Another thing is I would add a reference after the sentence describing the MOA of the b and y toxins.

-Structure: I don't have any big suggestions for this section. maybe you could hyperlink some of those terms pertaining to the protein structure including 3-finger structure, beta-pleated sheet, etc.